The Missouri Department of Health and Senior Services says that the state added 2,161 new cases of COVID-19 on Wednesday.
16 more people have died due to the virus.
The Arkansas Department of Health reports 1,703 new cases of COVID-19 on Wednesday.
Four additional people were placed on ventilators.
There are 1,064 total hospitalizations, adding 39 in one day.
Arkansas officials say that 12 more people have died.