Darrel Williams ran for a go-ahead, 1-yard touchdown with 23 seconds left for his second score in the fourth quarter, lifting the Kansas City Chiefs to a 34-30 win over the Detroit Lions.
Mahomes was 24 of 42 for 315 yards. The reigning MVP had thrown at least two touchdown passes in 14 straight games, one short of the NFL record set by Peyton Manning.
The Chiefs will host Indianapolis this Sunday night.
Other Games
New Orleans 12……………………….Dallas 10
Philadelphia 34…………………….Green Bay 27
NY Giants 24………………………Washington 3
Tennessee 24……………………….Atlanta 10
San Diego 30……………………….Miami 19
Seattle 27……………………………Arizona 10
Jacksonville 26………………………Denver 24
Oakland 31…………………………..Indianapolis 24
Cleveland 40…………………………Baltimore 28
New England 16……………………..Buffalo 10
Carolina 16……………………………Houston 10
Tampa Bay 55………………………..LA Rams 40
Chicago 16……………………………Minnesota 6
Tonight
Cincinnati is at Pittsburgh